Disseminated Aspergillosis Complicated With a Myocardial Abscess in an Immunodeficient Child

J Pediatr Hematol Oncol. 2021 Aug 1;43(6):226-227. doi: 10.1097/MPH.0000000000002078.

Abstract

Aspergillosis infection is a major complication of acquired immunosuppression, and is associated with poor prognosis in its invasive form. Cardiac dissemination of invasive aspergillosis is a rare and usually fatal consequence of systemic mycosis. We describe a pediatric case of myocardial aspergillosis abscess in a 12-year-old girl diagnosed with multimodality cardiac imaging approach. The patient underwent prolonged antimycotic treatment and bone marrow transplant, which improved her immunity, and, for the first time in the literature, resulted in a favorable outcome.

Publication types

  • Case Reports

MeSH terms

  • Abscess / etiology*
  • Abscess / pathology
  • Aspergillosis / complications*
  • Aspergillosis / pathology
  • Cardiomyopathies / etiology*
  • Cardiomyopathies / pathology
  • Child
  • Female
  • Humans
  • Immunologic Deficiency Syndromes / complications*
  • Immunologic Deficiency Syndromes / pathology
  • Myocardium / pathology*