RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner

Leukemia. 2021 Oct;35(10):2983-2988. doi: 10.1038/s41375-021-01268-4. Epub 2021 Jun 19.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Animals
  • Core Binding Factor Alpha 2 Subunit / physiology*
  • DNA-Binding Proteins / genetics*
  • Leukemia, Myeloid / genetics
  • Leukemia, Myeloid / metabolism
  • Leukemia, Myeloid / pathology*
  • Mice
  • Mice, Knockout
  • Oncogene Proteins, Fusion*
  • Proto-Oncogene Proteins / genetics*
  • RUNX1 Translocation Partner 1 Protein / physiology*
  • Transcription Factors / genetics*
  • Translocation, Genetic

Substances

  • Core Binding Factor Alpha 2 Subunit
  • DNA-Binding Proteins
  • MTG8 protein, mouse
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Proteins
  • RUNX1 Translocation Partner 1 Protein
  • Runx1 protein, mouse
  • Transcription Factors