Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.
Keywords: Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses.