An early assessment of a case fatality risk associated with P.1 SARS-CoV-2 lineage in Brazil: an ecological study

Shi Zhao; Jingzhi Lou; Lirong Cao; Hong Zheng; Zigui Chen; Renee W Y Chan; Benny C Y Zee; Paul K S Chan; Marc K C Chong; Maggie H Wang

doi:10.1093/jtm/taab078

An early assessment of a case fatality risk associated with P.1 SARS-CoV-2 lineage in Brazil: an ecological study

J Travel Med. 2021 Oct 11;28(7):taab078. doi: 10.1093/jtm/taab078.

Authors

Shi Zhao^{1

2}, Jingzhi Lou¹, Lirong Cao¹, Hong Zheng¹, Zigui Chen³, Renee W Y Chan^{4

5

6

7}, Benny C Y Zee^{1

2}, Paul K S Chan³, Marc K C Chong^{1

2}, Maggie H Wang^{1

2}

Affiliations

¹ JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
² CUHK Shenzhen Research Institute, Shenzhen, China.
³ Department of Microbiology, Chinese University of Hong Kong, Hong Kong, China.
⁴ Department of Paediatrics, Chinese University of Hong Kong, Hong Kong, China.
⁵ Hong Kong Hub of Pediatric Excellence, Chinese University of Hong Kong, Hong Kong, China.
⁶ CUHK-UMCU Joint Research Laboratory of Respiratory Virus and Immunobiology, Chinese University of Hong Kong, Hong Kong, China.
⁷ Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.

Abstract

The circulation of P.1 SARS-CoV-2 lineage becomes a challenge of pandemic control. Among the COVID-19 cases reported in Brazil, P.1 is estimated 54% more fatal than non-P.1 significantly. Considering the transmission advantage of P.1, we raise concerns regarding the rapid growth in critical patients.

Keywords: Brazil; COVID-19; P.1 lineage; case fatality; statistical modelling.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brazil
COVID-19*
Humans
Research
SARS-CoV-2*

Abstract

Publication types

MeSH terms

Grants and funding