ADHD symptomatology of children with congenital heart disease 10 years after cardiac surgery: the role of age at operation

BMC Psychiatry. 2021 Jun 24;21(1):316. doi: 10.1186/s12888-021-03324-w.

Abstract

Background: The aim of the present study was to investigate the differences in ADHD symptomatology between healthy controls and children who underwent cardiac surgery at different ages.

Methods: Altogether, 133 children (54 patients with congenital heart disease undergoing first cardiac surgery under 3 years of age, 26 operated at the age of 3 or later, and 53 healthy controls) were examined. Patients completed the Youth Self Report (YSR), while their parents completed the Child Behaviour Checklist (CBCL) and the ADHD Rating Scale-IV.

Results: Children receiving surgery for the first time under the age of 3 years were more likely diagnosed with cyanotic type malformation and have undergone to a greater number of operations. However, ADHD symptoms of those treated surgically at or above 3 years of age were more severe than that of the control group or those who were treated surgically at a younger age. The control group and those treated surgically below the age of three did not differ across any of the ADHD symptom severity indicators.

Conclusions: The age at the time of cardiac surgery might be associated with later ADHD symptom severity - with lower age at operation associated with better outcomes. Further, adequately powered studies are needed to confirm these exploratory findings and investigate the moderators of this relationship.

Keywords: Age-related differences; Attention-deficit hyperactivity disorder; Congenital heart disease; Pediatric cardiac surgery.

MeSH terms

  • Adolescent
  • Attention Deficit Disorder with Hyperactivity*
  • Cardiac Surgical Procedures* / adverse effects
  • Child
  • Child, Preschool
  • Heart Defects, Congenital* / complications
  • Heart Defects, Congenital* / surgery
  • Humans
  • Parents