Suprasellar craniopharyngioma associated with hyperprolactinemia, pituitary lactotroph hyperplasia, and microprolactinoma. Case report

J Neurosurg. 1988 Oct;69(4):620-3. doi: 10.3171/jns.1988.69.4.0620.

Abstract

A case with the coexistence of a microprolactinoma and suprasellar craniopharyngioma lactotroph hyperplasia is presented. Loss of inhibitory hypothalamic dopaminergic input may have played a role in hyperprolactinemia and the proliferation of pituitary lactotrophs. This is believed to be the first published case of suprasellar craniopharyngioma with this association.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / complications*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery
  • Combined Modality Therapy
  • Craniopharyngioma / complications*
  • Craniopharyngioma / pathology
  • Craniopharyngioma / surgery
  • Humans
  • Hyperplasia
  • Hyperprolactinemia / complications*
  • Male
  • Middle Aged
  • Pituitary Gland / metabolism
  • Pituitary Gland / pathology*
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / metabolism*
  • Prolactin / metabolism*
  • Sella Turcica

Substances

  • Prolactin