Toxicological Profile of Plasmonic Nanoparticles in Zebrafish Model

Int J Mol Sci. 2021 Jun 14;22(12):6372. doi: 10.3390/ijms22126372.

Abstract

Plasmonic nanoparticles are increasingly employed in several fields, thanks to their unique, promising properties. In particular, these particles exhibit a surface plasmon resonance combined with outstanding absorption and scattering properties. They are also easy to synthesize and functionalize, making them ideal for nanotechnology applications. However, the physicochemical properties of these nanoparticles can make them potentially toxic, even if their bulk metallic forms are almost inert. In this review, we aim to provide a more comprehensive understanding of the potential adverse effects of plasmonic nanoparticles in zebrafish (Danio rerio) during both development and adulthood, focusing our attention on the most common materials used, i.e., gold and silver.

Keywords: adulthood; development; gold; plasmonic nanoparticles; silver; toxicity; zebrafish.

Publication types

  • Review

MeSH terms

  • Animals
  • Models, Animal*
  • Nanoparticles / toxicity*
  • Particle Size
  • Toxicity Tests*
  • Zebrafish