Severe liver damage caused by therapeutic doses of acetaminophen

Acta Med Scand. 1987;222(3):285-8. doi: 10.1111/j.0954-6820.1987.tb10672.x.

Abstract

Two patients who ingested therapeutic doses of acetaminophen and who developed a severe hepatotoxicity are reported. Both patients had a rather high alcohol consumption, which probably made them susceptible to the toxic effects of acetaminophen.

Publication types

  • Case Reports

MeSH terms

  • Acetaminophen / administration & dosage
  • Acetaminophen / adverse effects*
  • Alanine Transaminase / blood
  • Alcohol Drinking
  • Aspartate Aminotransferases / blood
  • Chemical and Drug Induced Liver Injury*
  • Female
  • Humans
  • Liver Diseases / pathology
  • Middle Aged
  • Necrosis

Substances

  • Acetaminophen
  • Aspartate Aminotransferases
  • Alanine Transaminase