Contemporary Classification of Glucagon-Like Peptide 1 Receptor Agonists (GLP1RAs)

Sanjay Kalra; Saptarshi Bhattacharya; Nitin Kapoor

doi:10.1007/s13300-021-01113-y

Contemporary Classification of Glucagon-Like Peptide 1 Receptor Agonists (GLP1RAs)

Diabetes Ther. 2021 Aug;12(8):2133-2147. doi: 10.1007/s13300-021-01113-y. Epub 2021 Jul 15.

Authors

Sanjay Kalra¹, Saptarshi Bhattacharya², Nitin Kapoor^{3

4}

Affiliations

¹ Department of Endocrinology, Bharti Hospital, Karnal, India.
² Department of Endocrinology, Max Superspeciality Hospital, Patparganj, New Delhi, India.
³ Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India. [email protected].
⁴ Non Communicable Disease Unit, Melbourne School of Population and Global Health, University of Melbourne, Victoria, Australia. [email protected].

Abstract

This communication provides a contemporary classification of glucagon-like peptide 1 receptor agonists (GLP1RAs) based on indication, route, and frequency of administration, which could support a person-centric approach to treatment choice. It includes all recently developed GLP1RAs as well as those in advanced stages of clinical study. Keeping pace with current trends in pharmacology and metabolic medicine, it attempts to bring clarity and simplicity to a complex spread of information.

Keywords: Danuglipron; Dulaglutide; Exenatide; Exenatide LAR; GLP1RA; IDegLira; IcoSema; Liraglutide; LixiLan; Person-centric care; Semaglutide; Tirzepatide.

Publication types

Review