Evaluation of life expectancy loss associated with submicron and fine particulate matter (PM₁ and PM_2.5) air pollution in Nanjing, China

Particulate matters with an aerodynamic diameter ≤1 μm (PM₁) significantly increased mortality risk, and the effect of PM₁ was even greater than that of PM_2.5 (aerodynamic diameter ≤2.5 μm). But the quantitative impact of PM₁ on life expectancy was unknown. We aim to examine the extent to which that people's life expectancy was shortened by PM₁ and PM_2.5. We obtained daily data on deaths, PM₁ and PM_2.5 records, and weather variables during 2016-2017 in Nanjing, China. Years of life lost (YLLs) were calculated by matching each decedent's age and sex to the Chinese life table. The fitted nonlinear dose-response associations of YLLs with PM₁ and PM_2.5 were estimated by utilizing a generalized additive model with a Gaussian link that controlled for confounding factors including meteorological variables, day of week, and long-term trend and seasonality. The effect estimates were presented as the YLLs when PM₁ and PM_2.5 concentrations fell in different ranges. Life expectancy losses attributable to PM₁ and PM_2.5 were calculated. Stratified analyses were also performed by age, sex, and death causes. Significant PM-YLL associations were observed, with greater increases in YLLs associated with PM₁ (68.9 thousand). PM₁ was estimated to reduce life expectancy, which was greater than PM_2.5 (PM₁: 1.67 years; PM_2.5: 1.55 years). For PM₁, greater years of loss in PM-related life expectancy were found in the female group, ≥65 years group, and cardiovascular disease group. Exposure to PM₁ had a greater impact on life expectancy loss than did PM_2.5. Constant efforts are urgently needed to control PM₁ air pollution to improve people's longevity.