Local regulation of auxin transport in root-apex transition zone mediates aluminium-induced Arabidopsis root-growth inhibition

Plant J. 2021 Oct;108(1):55-66. doi: 10.1111/tpj.15424. Epub 2021 Jul 30.

Abstract

Aluminium (Al) stress is a major limiting factor for worldwide crop production in acid soils. In Arabidopsis thaliana, the TAA1-dependent local auxin biosynthesis in the root-apex transition zone (TZ), the major perception site for Al toxicity, is crucial for the Al-induced root-growth inhibition, while the mechanism underlying Al-regulated auxin accumulation in the TZ is not fully understood. In the present study, the role of auxin transport in Al-induced local auxin accumulation in the TZ and root-growth inhibition was investigated. Our results showed that PIN-FORMED (PIN) proteins such as PIN1, PIN3, PIN4 and PIN7 and AUX1/LAX proteins such as AUX1, LAX1 and LAX2 were all ectopically up-regulated in the root-apex TZ in response to Al stress and coordinately regulated local auxin accumulation in the TZ and root-growth inhibition. The ectopic up-regulation of PIN1 in the TZ under Al stress was regulated by both ethylene and auxin, with auxin signalling acting downstream of ethylene. Al-induced PIN1 up-regulation and auxin accumulation in the root-apex TZ was also regulated by the calossin-like protein BIG. Together, our results provide insight into how Al stress induces local auxin accumulation in the TZ and root-growth inhibition through the local regulation of auxin transport.

Keywords: PIN1; aluminium; auxin transport; root growth; root-apex transition zone.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum / toxicity*
  • Arabidopsis / drug effects
  • Arabidopsis / genetics
  • Arabidopsis / growth & development
  • Arabidopsis / physiology*
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Biological Transport
  • Calmodulin-Binding Proteins / genetics
  • Calmodulin-Binding Proteins / metabolism
  • Ethylenes / metabolism*
  • Gene Expression Regulation, Plant
  • Indoleacetic Acids / metabolism*
  • Membrane Transport Proteins / genetics
  • Membrane Transport Proteins / metabolism*
  • Plant Growth Regulators / metabolism*
  • Plant Roots / drug effects
  • Plant Roots / genetics
  • Plant Roots / growth & development
  • Plant Roots / metabolism
  • Stress, Physiological
  • Up-Regulation

Substances

  • Arabidopsis Proteins
  • BIG protein, Arabidopsis
  • Calmodulin-Binding Proteins
  • Ethylenes
  • Indoleacetic Acids
  • Membrane Transport Proteins
  • PIN1 protein, Arabidopsis
  • Plant Growth Regulators
  • ethylene
  • Aluminum

Associated data

  • RefSeq/NM_106017
  • RefSeq/NM_125091
  • RefSeq/NM_105762
  • RefSeq/NM_179592
  • RefSeq/NM_179369
  • RefSeq/NM_129368
  • RefSeq/NM_120202
  • RefSeq/NM_127675
  • RefSeq/NM_111093