Llibre and colleagues' brief research report investigated the effect of point-of-care onsite testing, use of face masks, and improved ventilation in preventing SARS-CoV-2 transmission at a large indoor concert. The editorialists evaluate factors that contributed to the success of these multimethod prevention strategies and the cost-effectiveness of such measures. They also consider how these measures could be adapted to prevent SARS-CoV-2 transmission in other settings.