Genetic counseling and screening of consanguineous couples and their offspring practice resource: Focused Revision

Robin L Bennett; Neeraja R Malleda; Peter H Byers; Robert D Steiner; Kimberly M Barr

doi:10.1002/jgc4.1477

Genetic counseling and screening of consanguineous couples and their offspring practice resource: Focused Revision

J Genet Couns. 2021 Oct;30(5):1354-1357. doi: 10.1002/jgc4.1477. Epub 2021 Jul 26.

Authors

Robin L Bennett¹, Neeraja R Malleda², Peter H Byers³, Robert D Steiner⁴, Kimberly M Barr⁵

Affiliations

¹ Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington, USA.
² LifeCell International Pvt. Ltd, Mumbai, Maharashtra, India.
³ Department of Laboratory Medicine and Pathology, Department of Medicine (Medical Genetics), University of Washington, Seattle, Washington, USA.
⁴ Marshfield Clinic Health System, Prevention Genetics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
⁵ Department of Genetics, Kaiser Permanente Medical Center, San Francisco, California, USA.

PMID: 34309119
DOI: 10.1002/jgc4.1477

Abstract

There are no evidence-based guidelines to inform genetic counseling for consanguineous couples and their offspring. This focused revision builds on the expert opinions from the original publication of "Genetic Counseling and Screening of Consanguineous Couples and Their Offspring," based on a review of literature published since 2002.

Keywords: SNP microarray; consanguinity; genetic counselling; genetic screening; genetic testing; incest; newborn screening; tandem mass spectrometry.

Publication types

Review

MeSH terms

Consanguinity
Family*
Genetic Counseling*
Humans
Mass Screening