Extranodal Rosai-Dorfman Disease Presenting as a Pericardial Mass and Constrictive Pericarditis

Chirag K Desai; Sharonne N Hayes; Mithun Vinod Shah; Joseph J Maleszewski; Jonathan Bleeker; Kelly Steffen; Maria Stys

doi:10.1016/j.jaccas.2019.10.011

Extranodal Rosai-Dorfman Disease Presenting as a Pericardial Mass and Constrictive Pericarditis

JACC Case Rep. 2019 Dec 4;1(4):643-647. doi: 10.1016/j.jaccas.2019.10.011. eCollection 2019 Dec.

Authors

Chirag K Desai¹, Sharonne N Hayes², Mithun Vinod Shah³, Joseph J Maleszewski^{2

4}, Jonathan Bleeker⁵, Kelly Steffen¹, Maria Stys¹

Affiliations

¹ Division of Cardiovascular Disease, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
² Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
³ Division of Hematology, Mayo Clinic, Rochester, Minnesota.
⁴ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
⁵ Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Abstract

Rosai-Dorfman disease is a rare, idiopathic disorder of histiocyte proliferation. We describe a case of a 59-year-old woman who presented with heart failure symptoms from a large pericardial mass causing constrictive pericarditis. Pathologic findings including immunohistochemistry suggested the diagnosis. She was treated with corticosteroids and improved clinically. (Level of Difficulty: Advanced.).

Keywords: FDG, fluorodeoxyglucose; RDD, Rosai-Dorfman disease; cardiac; constriction; corticosteroids; heart failure; sinus histiocytosis.

Publication types

Case Reports