Kounis Syndrome Leading to Cardiac Arrest After Iodinated Contrast Exposure

JACC Case Rep. 2020 Apr 15;2(4):626-629. doi: 10.1016/j.jaccas.2019.12.044. eCollection 2020 Apr.

Abstract

Immune-mediated coronary spasm, called Kounis syndrome (KS), is not rare but is underdiagnosed. In this report, we present a case of KS induced by iodinated contrast resulting in cardiac arrest, requiring temporary mechanical circulatory support. We show angiographic evidence of KS and outline commonly associated clinical features that may predict KS. (Level of Difficulty: Beginner.).

Keywords: ACS, acute coronary syndrome; AOPP, advanced oxidation protein products; ED, emergency department; FFR, fraction flow reserve; KS, Kounis syndrome; Kounis syndrome; PEA arrest; VA-ECMO, venoarterial extracorporeal membrane oxygenation; allergic reaction; anaphylaxis.

Publication types

  • Case Reports