Acute Myocardial Dysfunction and Hypereosinophilic Infiltrative Myocarditis Secondary to New-Onset Pediatric Acute Lymphoblastic Leukemia

JACC Case Rep. 2021 Jul 7;3(7):991-996. doi: 10.1016/j.jaccas.2021.03.017.

Abstract

Myocardial infiltration by eosinophils leads to myocardial inflammation and fibrosis, resulting in restrictive hemodynamics. We describe an uncommon presentation of eosinophilic predominant acute lymphoblastic leukemia that manifested with hypereosinophilic infiltrative myocarditis. (Level of Difficulty: Advanced.).

Keywords: ALL, acute lymphoblastic leukemia; CMR, cardiac magnetic resonance; CT, computed tomography; EF, ejection fraction; HD, hospital day; LV, left ventricular; acute lymphoblastic leukemia; eosinophilia; myocarditis; pediatric.

Publication types

  • Case Reports