Clinical Profile and Outcome of Emergencies in Pediatric Chronic Kidney Disease

Indian Pediatr. 2022 Jan 15;59(1):31-34. Epub 2021 Aug 2.

Abstract

Objective: To describe the clinical profile and outcome of emergencies in children with chronic kidney disease (CKD).

Methods: This retrospective analysis studied children with CKD presenting with acute emergencies. The clinical profile, renal and patient outcomes were compared between incidentally diagnosed - iCKD, previously diagnosed not on dialysis - pCKD and those on maintenance dialysis - dCKD groups.

Results: 82 children (67 boys, median age - 8 years) with 99 visits were included. Uremic encephalopathy was the most common emergency in iCKD (64.7%) and pCKD (38.4 %), and access-related infections (32.1%) in dCKD group. Children with iCKD had higher Pediatric Risk of Mortality score (P<0.001), emergent initiation of dialysis (P=0.03) and discontinuation of treatment (P<0.001) when compared to the pCKD group.

Conclusion: Uremic encephalopathy and access-related infections were the most common emergencies in children with CKD. Incidentally diagnosed CKD had a worse clinical profile and outcome.

MeSH terms

  • Child
  • Emergencies*
  • Humans
  • Kidney
  • Male
  • Renal Dialysis
  • Renal Insufficiency, Chronic* / epidemiology
  • Renal Insufficiency, Chronic* / therapy
  • Retrospective Studies