A Review of the Cardiac and Cardiovascular Effects of COVID-19 in Adults and Children

Bibhuti B Das; S Kristen Sexon Tejtel; Shriprasad Deshpande; Lara S Shekerdemian

doi:10.14503/THIJ-20-7395

A Review of the Cardiac and Cardiovascular Effects of COVID-19 in Adults and Children

Tex Heart Inst J. 2021 Jul 1;48(3):e207395. doi: 10.14503/THIJ-20-7395.

Authors

Bibhuti B Das¹, S Kristen Sexon Tejtel¹, Shriprasad Deshpande², Lara S Shekerdemian³

Affiliations

¹ Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.
² Department of Pediatrics, Children's National Hospital, The George Washington University, Washington, DC.
³ Division of Critical Care, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.

Abstract

Symptomatic coronavirus disease 2019 (COVID-19) typically affects the respiratory system but can involve the cardiovascular system. Cardiac complications of COVID-19 can result directly from myocarditis or indirectly from numerous other mechanisms. Differentiating between primary and secondary cardiovascular involvement-our focus in this review-may help to identify the long-term effects of COVID-19 on the heart in adults and children.

Keywords: Angiotensin-converting enzyme 2; COVID-19/complications; SARS-CoV-2; biomarkers; cardiovascular diseases/epidemiology/etiology/physiopathology/virology; comorbidity; coronavirus infections/complications; cytokines/blood; disease progression; myocarditis/etiology.

Publication types

Comment

MeSH terms

Adult
COVID-19*
Cardiovascular Diseases* / diagnosis
Cardiovascular Diseases* / epidemiology
Cardiovascular Diseases* / etiology
Cardiovascular System*
Child
Heart
Humans
Myocarditis* / diagnosis
Myocarditis* / epidemiology
SARS-CoV-2