SARS-CoV-2-derived fusion inhibitor lipopeptides exhibit highly potent and broad-spectrum activity against divergent human coronaviruses

Signal Transduct Target Ther. 2021 Aug 3;6(1):294. doi: 10.1038/s41392-021-00698-x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents* / chemistry
  • Antiviral Agents* / pharmacology
  • COVID-19 / metabolism*
  • COVID-19 Drug Treatment*
  • Coronavirus Infections / drug therapy*
  • Coronavirus Infections / metabolism
  • Humans
  • Lipopeptides* / chemistry
  • Lipopeptides* / pharmacology
  • Middle East Respiratory Syndrome Coronavirus* / chemistry
  • Middle East Respiratory Syndrome Coronavirus* / metabolism
  • SARS-CoV-2* / chemistry
  • SARS-CoV-2* / metabolism
  • Virus Internalization / drug effects*

Substances

  • Antiviral Agents
  • Lipopeptides