[Pharmacobezoar in a woman with a clomipramine intoxication]

Ned Tijdschr Geneeskd. 2021 May 25:165:D5472.
[Article in Dutch]

Abstract

Background: Medicines with controlled release can cause a rare phenomenon, known as pharmacobezoar, following overdose of these medications.

Case description: A case of a 56-year-old women with severe clomipramine intoxication is described. X-ray of the abdomen showed a cluster of tablets in the caecum. Lab results showed severe plasma concentration of clomipramine. Patient was treated with active coal and remained stable.

Conclusion: It is important to be aware of the presence of pharmacobezoar in intoxication with controlled release medicines. The formation of pharmacobezoar can lead to unpredictable duration of intoxication.

Publication types

  • Case Reports

MeSH terms

  • Bezoars* / chemically induced
  • Clomipramine
  • Delayed-Action Preparations
  • Drug Overdose*
  • Female
  • Humans
  • Middle Aged
  • Stomach

Substances

  • Delayed-Action Preparations
  • Clomipramine