Lung Diseases Unique to Women

Rachel N Criner; Abdullah Al-Abcha; Allison A Lambert; MeiLan K Han

doi:10.1016/j.ccm.2021.04.014

Lung Diseases Unique to Women

Clin Chest Med. 2021 Sep;42(3):507-516. doi: 10.1016/j.ccm.2021.04.014.

Authors

Rachel N Criner¹, Abdullah Al-Abcha², Allison A Lambert³, MeiLan K Han⁴

Affiliations

¹ Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
² Department of Internal Medicine, Michigan State University, East Lansing, MI, USA.
³ Department of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA, USA; Providence Medical Research Center, Spokane, WA, USA.
⁴ Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: [email protected].

Abstract

The differences in the respiratory system between women and men begin in utero. Biologic sex plays a critical role in fetal development, airway anatomy, inhalational exposures, and inhaled particle deposition of the respiratory system, thus leading to differences in risk for disease, as well as clinical manifestations, morbidity, and mortality. In this article, we focus on those respiratory diseases unique to females: lymphangioleiomyomatosis and thoracic endometriosis syndrome.

Keywords: Endometriosis; Lymphangioleiomyomatosis; Sirolimus; Women.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Female
Humans
Lung Diseases* / etiology
Lung Diseases* / therapy
Lymphangioleiomyomatosis* / diagnosis
Lymphangioleiomyomatosis* / epidemiology
Lymphangioleiomyomatosis* / therapy
Male
Sirolimus

Substances

Sirolimus

Grants and funding

K24 HL138188/HL/NHLBI NIH HHS/United States