Hyperdiluted calcium hydroxylapatite for the treatment of skin laxity of the neck

Dermatol Ther. 2021 Sep;34(5):e15090. doi: 10.1111/dth.15090. Epub 2021 Aug 12.

Abstract

Despite being a common concern, there are very few minimally invasive treatments targeting neck skin laxity (NSL) reported in the literature. To assess the efficacy of hyperdiluted calcium hydroxyapatite (hy-CaHA) for the treatment of NSL, according to the NSL scale, and to estimate safety. Twenty patients showing NSL were treated with hy-CaHA 1:2. To evaluate the efficacy of hy-CaHA treatment for NSL, pictures of treated subjects were collected before and 3 months after treatment and graded according to the NSL scale, and T-student's test was applied to estimate differences. Hy-CaHA for the neck was effective according to the previously unreported NSL scale (p < 0.001) and safe. There were no major adverse events reported. This study supports the efficacy (according to the NSL scale) and safety of hy-CaHA (1:2) for NSL. Our results also highlight the utility of the newly developed NSL scale, being a useful tool to evaluate the level of NSL before treatment and to measure the outcome.

Keywords: calcium hydroxylapatite; hyperdiluted calcium hydroxylapatite; neck; neck skin laxity; skin laxity.

MeSH terms

  • Biocompatible Materials
  • Calcium
  • Cosmetic Techniques* / adverse effects
  • Durapatite
  • Humans
  • Neck
  • Skin
  • Skin Aging*

Substances

  • Biocompatible Materials
  • Durapatite
  • Calcium