Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans

Affiliations

• ¹ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ² Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
• ³ Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
• ⁴ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. [email protected].
• ⁵ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. [email protected].
• ⁶ Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, USA.
• ⁷ Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, USA.
• ⁸ Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
• ⁹ Institute for Molecular Medicine Finland, Helsinki, Finland.
• ¹⁰ Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ¹¹ Centre for Translational Bioinformatics, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London and Barts Health NHS Trust, London, UK.
• ¹² Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ¹³ National Heart & Lung Institute and MRC London Institute of Medical Sciences, Imperial College London, London, UK.
• ¹⁴ Cardiovascular Research Centre, Royal Brompton & Harefield Hospitals NHS Trust, London, UK.
• ¹⁵ Department of Pediatrics, University of Washington, Seattle, WA, USA.
• ¹⁶ Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
• ¹⁷ Vertex Pharmaceuticals Inc, Boston, MA, USA.
• ¹⁸ Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
• ¹⁹ Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
• ²⁰ Broad Genomics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ²¹ Department of Neurology, Harvard Medical School, Boston, MA, USA.
• ²² Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. [email protected].
• ²³ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. [email protected].
• ²⁴ Centre for Population Genomics, Garvan Institute of Medical Research, and UNSW Sydney, Sydney, New South Wales, Australia. [email protected].
• ²⁵ Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. [email protected].