Catheter-related bloodstream infection due to biofilm-producing Capnocytophaga sputigena

Shelcie Fabre; Yesha Malik; Adriana van De Guchte; Lourdes A Delgado-Noguera; Melissa R Gitman; Michael D Nowak; Emilia M Sordillo; Matthew M Hernandez; Alberto E Paniz-Mondolfi

doi:10.1016/j.idcr.2021.e01231

Catheter-related bloodstream infection due to biofilm-producing Capnocytophaga sputigena

IDCases. 2021 Jul 24:25:e01231. doi: 10.1016/j.idcr.2021.e01231. eCollection 2021.

Authors

Shelcie Fabre¹, Yesha Malik², Adriana van De Guchte³, Lourdes A Delgado-Noguera^{4

5

6}, Melissa R Gitman^{1

7}, Michael D Nowak^{1

7}, Emilia M Sordillo^{1

7}, Matthew M Hernandez⁷, Alberto E Paniz-Mondolfi^{1

7}

Affiliations

¹ Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
² Department of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
³ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
⁴ Infectious Diseases Division, Venezuelan Research Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Lara, 3001, Venezuela.
⁵ Instituto de Investigaciones Biomédicas IDB, Barquisimeto, Lara, 3001, Venezuela.
⁶ Health Sciences Department, College of Medicine, Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Lara, 3001, Venezuela.
⁷ Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

Abstract

Capnocytophaga sputigena is a facultatively-anaerobic bacterium that is part of the human oropharyngeal microflora. Although C. sputigena bacteremia is uncommon, systemic infections have been reported in both immunocompetent and immunocompromised patients. We report a case of catheter-related bloodstream infection by C. sputigena and highlight its enhanced biofilm-forming capacity in vitro.

Keywords: Bacteremia; Biofilm; Capnocytophaga sputigena; Central catheter.

Publication types

Case Reports