Inappropriate requesting of parathyroid scintigraphy at an academic medical center

Head Neck. 2021 Nov;43(11):3404-3407. doi: 10.1002/hed.26839. Epub 2021 Aug 11.

Abstract

Background: Primary hyperparathyroidism is a biochemical, not radiologic diagnosis. Parathyroid scintigraphy should only be requested for surgical planning, not to confirm diagnosis. Here we determined reasons for inappropriately ordered parathyroid scintigraphy.

Methods: We generated a database of patients undergoing parathyroid scintigraphy over 5 years, who did not undergo parathyroidectomy.

Results: Over 5 years 129 parathyroid scintigraphies (of 308 total scans) were performed in patients who did not undergo parathyroidectomy. We determined that only 58 (45%) had true primary hyperparathyroidism. The most common reason for the scan was to "confirm the diagnosis." Only 20% were ordered for adenoma localization, although surgery was not performed. Physicians requesting parathyroid scintigraphies specialized in a variety of disciplines.

Conclusion: Forty-two percent of parathyroid scintigraphies were requested inappropriately to "confirm" a diagnosis of primary hyperparathyroidism. We propose to change the ordering system to clarify that parathyroid scintigraphy is a functional tool to optimize surgery when the diagnosis is secure.

Keywords: parathyroid adenoma; preoperative localization; primary hyperparathyroidism; scintigraphy; secondary hyperparathyroidism.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Academic Medical Centers
  • Humans
  • Hyperparathyroidism, Primary* / diagnostic imaging
  • Hyperparathyroidism, Primary* / surgery
  • Parathyroid Glands / diagnostic imaging
  • Parathyroid Glands / surgery
  • Parathyroid Neoplasms* / diagnostic imaging
  • Parathyroid Neoplasms* / surgery
  • Parathyroidectomy
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi