A late diagnosis of Pseudohypoaldosteronism type I in an infant with hypoplastic left heart syndrome presenting with failure to thrive

Deani H McVadon; John M Costello; Katherine E Twombley; Sinai C Zyblewski

doi:10.1017/S1047951121003127

A late diagnosis of Pseudohypoaldosteronism type I in an infant with hypoplastic left heart syndrome presenting with failure to thrive

Cardiol Young. 2022 Mar;32(3):491-493. doi: 10.1017/S1047951121003127. Epub 2021 Aug 12.

Authors

Deani H McVadon¹, John M Costello¹, Katherine E Twombley², Sinai C Zyblewski¹

Affiliations

¹ Division of Pediatric Cardiology, Department of Pediatrics, Medical University of South Carolina, 10 McClennan Banks Dr, Charleston, SC, USA.
² Division of Pediatric Nephrology, Department of Pediatrics, Medical University of South Carolina, 10 McClennan Banks Dr, Charleston, SC, USA.

PMID: 34382535
DOI: 10.1017/S1047951121003127

Abstract

Pseudohypoaldosteronism type I is caused by a peripheral resistance to aldosterone and can present with electrolyte abnormalities, poor growth, or dehydration. Although a rare disease, several case reports have been published regarding Pseudohypoaldosteronism type I in neonates and infants. We report a case of failure to thrive and hyponatremia in an infant with hypoplastic left heart syndrome who was subsequently found to have Pseudohypoaldosteronism type I.

Keywords: Pseudohypoaldosteronism; failure to thrive; hyponatraemia; hypoplastic left heart syndrome.

Publication types

Case Reports

MeSH terms

Delayed Diagnosis
Failure to Thrive / etiology
Humans
Hyponatremia* / complications
Hyponatremia* / diagnosis
Hypoplastic Left Heart Syndrome* / complications
Hypoplastic Left Heart Syndrome* / diagnosis
Infant
Infant, Newborn
Pseudohypoaldosteronism* / diagnosis
Pseudohypoaldosteronism* / etiology