[A case of acute lymphoblastic leukemia of MTHFR C677T gene positive with methotrexate hypersensitivity was successfully rescued by hemodialysis]

Zhonghua Xue Ye Xue Za Zhi. 2021 Jun 14;42(6):524. doi: 10.3760/cma.j.issn.0253-2727.2021.06.016.

[Article in Chinese]

Authors

L W Ren¹, T Wu¹, F Xue¹, W H Liu¹, D F Mao¹, L L Yu¹, Z H Wang¹, H Bai¹

Affiliation

¹ The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.

PMID: 34384163
PMCID: PMC8295620
DOI: 10.3760/cma.j.issn.0253-2727.2021.06.016

No abstract available

Publication types

Case Reports

MeSH terms

Antimetabolites, Antineoplastic / therapeutic use
Genetic Predisposition to Disease
Genotype
Humans
Methotrexate*
Methylenetetrahydrofolate Reductase (NADPH2) / genetics
Polymorphism, Single Nucleotide
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / genetics
Renal Dialysis

Substances

Antimetabolites, Antineoplastic
MTHFR protein, human
Methylenetetrahydrofolate Reductase (NADPH2)
Methotrexate