Intratumoral Heterogeneity in a Patient With Metastatic Thymic Carcinoma on 18F-FDG, 68Ga-DOTATATE, and 68Ga-FAPI04 PET/CT

Clin Nucl Med. 2022 Jan 1;47(1):e79-e80. doi: 10.1097/RLU.0000000000003843.

Abstract

Herein, we present a 72-year-old woman with metastatic thymic carcinoma, referred for salvage peptide receptor radionuclide therapy with 177Lu-DOTATATE after completing all treatment options according to current clinical practice and guidelines. However, the patient was not eligible for 177Lu-DOTATATE peptide receptor radionuclide therapy and underwent 68Ga-FAPI04 PET/CT to assess the potential for a FAP-targeted therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography
  • Radionuclide Imaging
  • Thymoma*
  • Thymus Neoplasms* / diagnostic imaging

Substances

  • Organometallic Compounds
  • copper dotatate CU-64
  • Fluorodeoxyglucose F18