Identification and genetic characterization of a NUP98-HHEX molecular rearrangement in a pediatric acute myeloid leukemia

Leuk Lymphoma. 2021 Dec;62(14):3531-3535. doi: 10.1080/10428194.2021.1966784. Epub 2021 Aug 17.

Authors

Nathalie Sorel¹, Anna Raimbault^{1

2}, Françoise Brizard², Thibault Depaire², Valentina Pierini³, Christelle Dupraz⁴, Frédéric Millot⁴, Cristina Mecucci³, Jean-Claude Chomel¹

Affiliations

¹ Department of Cancer Biology, Onco-Hematology Unit, CHU Poitiers, Poitiers, France.
² Hematology Laboratory, CHU Poitiers, Poitiers, France.
³ Section of Hematology and Center for Hemato-Oncology Research, University of Perugia, Perugia, Italy.
⁴ Pediatric Oncology Unit, CIC 1402 INSERM, CHU Poitiers, Poitiers, France.

PMID: 34399652
DOI: 10.1080/10428194.2021.1966784

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
Homeodomain Proteins / genetics
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Nuclear Pore Complex Proteins / genetics
Oncogene Proteins, Fusion / genetics
Transcription Factors / genetics
Translocation, Genetic

Substances

HHEX protein, human
Homeodomain Proteins
Nuclear Pore Complex Proteins
Nup98 protein, human
Oncogene Proteins, Fusion
Transcription Factors