Exacerbation of connective tissue disease-associated interstitial lung disease due to influenza vaccination

Vaccinations against influenza viruses are widely used all over the world. There are reports, however, of some associated adverse events, and there are some case reports of interstitial lung disease occurring after influenza vaccination. We experienced the case of exacerbation of connective tissue disease-associated interstitial lung disease (CTD-ILD) after influenza vaccination, and this is the first reported case, as far as we know. The patient responded quite well to corticosteroids administration. Influenza vaccination for patients with chronic lung disease including CTD-ILD is strongly recommended, but we should be aware of possible adverse events.