Building population models for large-scale neural recordings: Opportunities and pitfalls

Curr Opin Neurobiol. 2021 Oct:70:64-73. doi: 10.1016/j.conb.2021.07.003. Epub 2021 Aug 17.

Abstract

Modern recording technologies now enable simultaneous recording from large numbers of neurons. This has driven the development of new statistical models for analyzing and interpreting neural population activity. Here, we provide a broad overview of recent developments in this area. We compare and contrast different approaches, highlight strengths and limitations, and discuss biological and mechanistic insights that these methods provide.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Neurons* / physiology