Sebaceous adenoma of the conjunctiva and caruncle: a clinicopathological report of three cases and literature review

Arq Bras Oftalmol. 2021 Aug 18;85(2):174-177. doi: 10.5935/0004-2749.20220023. eCollection 2021.

Abstract

Sebaceous tumors of the conjunctiva and caruncle are rare conditions, accounting for 1% of caruncle lesions and even lower among conjunctival lesions. Almost 50% of cases are associated with Muir-Torre syndrome, a rare autosomal-dominant condition characterized by at least one sebaceous skin tumor and one visceral malignancy. We report 3 cases of sebaceous adenoma with different presentations that were submitted to excisional biopsy and immunohistochemical study. Diagnosis of these tumors should increase the level of suspicion and lead to clinical investigation to rule out neoplasms, particularly because in up to 41% of cases, these can be the first sign of the disease.

Publication types

  • Case Reports
  • Letter
  • Review

MeSH terms

  • Adenoma* / surgery
  • Conjunctiva / pathology
  • Humans
  • Muir-Torre Syndrome* / diagnosis
  • Sebaceous Gland Neoplasms* / surgery