Validation of an At-Home Direct Antigen Rapid Test for COVID-19

Alexander Harmon; Celina Chang; Nol Salcedo; Brena Sena; Bobby Brooke Herrera; Irene Bosch; Laura E Holberger

doi:10.1001/jamanetworkopen.2021.26931

Validation of an At-Home Direct Antigen Rapid Test for COVID-19

JAMA Netw Open. 2021 Aug 2;4(8):e2126931. doi: 10.1001/jamanetworkopen.2021.26931.

Authors

Alexander Harmon¹, Celina Chang², Nol Salcedo¹, Brena Sena¹, Bobby Brooke Herrera^{1

3}, Irene Bosch^{1

4}, Laura E Holberger⁵

Affiliations

¹ E25Bio, Inc, Cambridge, Massachusetts.
² LabCentral, Inc, Cambridge, Massachusetts.
³ Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
⁴ Department of Medicine, Mount Sinai School of Medicine, New York, New York.
⁵ BioLabs (BioInnovation Labs, LLC), Cambridge, Massachusetts.

Abstract

This cohort study examines the performance of direct antigen rapid tests compared with that of quantitative real-time polymerase chain reaction for analyzing self-collected nasal specimens for the presence of SARS-CoV-2.

Publication types

Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Adult
Aged
Antigens, Viral*
COVID-19 / diagnosis*
COVID-19 / virology
COVID-19 Testing*
Direct-To-Consumer Screening and Testing / methods*
Female
Humans
Male
Mass Screening / methods*
Middle Aged
SARS-CoV-2* / immunology
Self-Testing
Sensitivity and Specificity
Young Adult

Substances

Antigens, Viral