[Prognostic factors in cerebral hypoxic-ischemias in infants less than a year old]

Arch Fr Pediatr. 1987 Dec;44(10):833-8.
[Article in French]

Abstract

In order to establish criteria for early cerebral prognosis after acute cerebral hypoxic ischemic insult, we studied 31 cases of patients presenting, during their first year of life, cardio-respiratory arrests due to SIDS (21 cases), anesthesia (4 cases), other causes (6 cases). A favourable evolution was observed in 5 cases where coma lasted less than 8 hours. Conversely unfavorable evolution was seen in the 26 patients (21 deaths, 5 sequellae) where coma lasted more than 8 hours. Among 12 patients of this group surviving after the 4th day, 9 expressed seizures or status epilepticus. The poor evolution was correlated with hyperproteinorachia during the first 24 hours and with cortico-subcortical hypodensity on CT scan. Early EEG and transfontanellar echography seemed less useful to establish a prognosis, specifically to discriminate children surviving with and without sequelae.

Publication types

  • English Abstract

MeSH terms

  • Brain Ischemia / complications
  • Brain Ischemia / physiopathology*
  • Cerebrospinal Fluid Proteins / analysis
  • Creatine Kinase / blood
  • Echoencephalography
  • Electroencephalography
  • Female
  • Heart Arrest / etiology
  • Humans
  • Hypoxia, Brain / complications
  • Hypoxia, Brain / physiopathology*
  • Infant
  • Infant, Newborn
  • Male
  • Prognosis
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Cerebrospinal Fluid Proteins
  • Creatine Kinase