Imaging and serological approaches play an important role in the diagnosis and treatment of alveolar echinococcosis; however, they also suffer from some problems during their applications in clinical practices, which urges the identification of potential diagnostic markers. Novel serological, genomics and proteomics diagnostic markers alone or in combination may increase the sensitivity and specificity in early diagnosis of alveolar echinococcosis, which play vital roles in monitoring of disease courses and prognostic evaluation. This review mainly presents the advances in the studies on novel diagnostic markers for alveolar echinococcosis.
［摘要］ 影像学与血清学技术在多房棘球蚴病诊断、治疗与评价中扮演着重要角色, 但其在临床应用中的一些不足促使 研究者对潜在诊断标志物进行探索。基于血清学、基因组学及蛋白质组学的新型诊断标志物单独或联合应用有望提高 多房棘球蚴病早期诊断的灵敏度与特异度, 在后续病程监测与预后评估中发挥重要作用。本文主要就多房棘球蚴病新 型诊断标志物研究进展作一综述。.
Keywords: Alveolar echinococcosis; Circulating free DNA; Diagnostic marker; MicroRNA; Proteomics.