St. John's Wort (Hypericum perforatum)-Related Acute Kidney Injury

Blood Purif. 2022;51(6):520-522. doi: 10.1159/000518349. Epub 2021 Aug 24.

Abstract

Some herbal products were reported to cause nephrotoxicity through different mechanisms. This case report defines an acute kidney injury (AKI) in a patient who used Hypericum perforatum tea as a sleep disorder remedy. The patient developed AKI after ingestion of tea prepared from Hypericum perforatum and underwent hemodialysis because of acute kidney failure. After 1 week, the kidney recovered, and she was discharged with normal kidney function. This is the first case reported having acute kidney failure caused by ingestion of Hypericum perforatum.

Keywords: Acute kidney injury; Hemodialysis; Nephrotoxicity; St. John’s wort.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury* / chemically induced
  • Acute Kidney Injury* / therapy
  • Female
  • Humans
  • Hypericum* / adverse effects
  • Phytotherapy
  • Plant Extracts / adverse effects
  • Tea

Substances

  • Plant Extracts
  • Tea