Abstract
CBFB-MYH11 transcripts and KIT mutations predict relapse in AML.
High-risk CBFB-MYH11 transcripts are associated with distinct transcriptional landscapes and upregulation of early hematopoiesis genes.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Core Binding Factor beta Subunit
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Humans
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Leukemia, Myeloid, Acute* / diagnosis
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Leukemia, Myeloid, Acute* / genetics
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Myosin Heavy Chains
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Oncogene Proteins, Fusion / genetics
Substances
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CBFB protein, human
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Core Binding Factor beta Subunit
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MYH11 protein, human
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Oncogene Proteins, Fusion
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Myosin Heavy Chains