Nephron Sparing Surgery in Bilateral Wilms Tumors With Botryoid Growth Pattern

J Pediatr Hematol Oncol. 2022 Apr 1;44(3):e740-e742. doi: 10.1097/MPH.0000000000002337.

Abstract

Botryoid growth pattern (BGP) is a polypoid mass growing into the renal pelvis, rarely seen in bilateral Wilms tumors where it represents a surgical challenge. We report our experience of nephron sparing surgery in 3 patients with BGP in bilateral Wilms tumor. Surgical en bloc removal was performed after calyx opening with no complications. The histology of the BGP was Intralobar Nephrogenic Rest in all cases while all Wilms tumors were of intermediate risk. One patient early recurred. At a follow-up of 9 months, 22 and 23 years, all patients were alive with a moderate renal insufficiency and hypertension.

MeSH terms

  • Female
  • Humans
  • Kidney Neoplasms* / pathology
  • Kidney Neoplasms* / surgery
  • Male
  • Neoplasm Recurrence, Local / surgery
  • Nephrectomy
  • Nephrons / pathology
  • Nephrons / surgery
  • Retrospective Studies
  • Wilms Tumor* / pathology
  • Wilms Tumor* / surgery