Acute Pancreatitis: The Increasing Role of Medical Management of a Traditionally Surgically Managed Disease

Am J Med. 2022 Feb;135(2):167-172. doi: 10.1016/j.amjmed.2021.08.021. Epub 2021 Sep 22.

Abstract

Management of acute pancreatitis and its complications has rapidly evolved in recent years. The earlier pillars of management that included prolonged bowel rest, empiric intravenous antibiotics, and early surgical intervention for complications such as pancreatic necrosis have become much less common. The latest evidence-based approaches to acute pancreatitis are taking almost a diametrically different path to previous management. The current strategy focuses on early feeding, judicious use of antibiotics, and delayed use of invasive interventions. Even in complex cases, when surgical interventions may be indicated, there is an expressed preference for minimally invasive techniques. We review the changes that have evolved rapidly over the past decade in this common clinical problem.

Keywords: Endoscopic drainage; Lipase; Pancreatic necrosis; Pancreatitis; Pseudocyst.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Drainage / methods
  • Humans
  • Minimally Invasive Surgical Procedures
  • Pancreatitis / diagnosis*
  • Pancreatitis / therapy*