Acupuncture as adjunctive therapy for acute renal colic caused by urinary calculi: study protocol for a randomized controlled trial

Trials. 2021 Sep 25;22(1):652. doi: 10.1186/s13063-021-05600-2.

Abstract

Background: Acute renal colic caused by urinary calculi (ARCUC) has a considerable impact on the quality of life. Acupuncture might be a potential treatment option. However, the evidence is limited. We will conduct this trial to evaluate the efficacy and safety of acupuncture as adjunctive treatment to diclofenac for ARCUC.

Methods/design: A total of 80 eligible patients who are diagnosed with urinary stone renal colic will be randomly allocated to the acupuncture group or the sham acupuncture group. Each patient will receive 1 session of acupuncture or sham acupuncture. The primary outcome will be the response rate of patients achieving a reduction of > 50% on visual analog score (VAS) from baseline to 10 min after treatment. Secondary outcomes will include the VAS, remedial analgesia, re-visit and admission rate, blinding assessment, credibility and expectancy, and adverse event. All patients who receive randomization will be included in the intent-to-treat analysis.

Discussion: The finding of this trial will provide evidence on the efficacy and safety of acupuncture for the treatment of ARCUC. The results of this study will be published in peer-reviewed journals.

Trial registration: ClinicalTrials.gov ChiCTR 1900025202 . Registered on August 16, 2019.

Keywords: Acupuncture; Acute renal colic; Randomized controlled trial; Sham acupuncture; Urinary calculi.

Publication types

  • Clinical Trial Protocol

MeSH terms

  • Acupuncture Therapy* / adverse effects
  • Humans
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Renal Colic* / diagnosis
  • Renal Colic* / etiology
  • Renal Colic* / therapy
  • Treatment Outcome
  • Urinary Calculi*