The effect of oxalic acid on the aggregability of human platelet rich plasma

Prostaglandins Leukot Med. 1986 Jan;21(1):107-10. doi: 10.1016/0262-1746(86)90168-x.

Abstract

Human platelet aggregation induced by ADP was studied after incubation with urea, methylguanidine, creatinine and oxalic acid. Oxalic acid significantly (p less than 0.05) inhibits human thrombocyte aggregation. Physiopathological implications are discussed.

MeSH terms

  • Adenosine Diphosphate / pharmacology
  • Adolescent
  • Creatinine / pharmacology
  • Humans
  • Methylguanidine / pharmacology
  • Oxalates / pharmacology*
  • Oxalic Acid
  • Platelet Aggregation / drug effects*
  • Urea / pharmacology
  • Uremia / blood

Substances

  • Oxalates
  • Methylguanidine
  • Adenosine Diphosphate
  • Urea
  • Oxalic Acid
  • Creatinine