Calcification of Gore-Tex Neochord After Mitral Repair: Electron Microscopy

Ann Thorac Surg. 2022 Jul;114(1):e1-e3. doi: 10.1016/j.athoracsur.2021.08.057. Epub 2021 Sep 29.

Abstract

A 76-year-old woman presented with severe mitral valve regurgitation 6 years after mitral valve repair with Gore-Tex (expanded polytetrafluoroethylene, W.L. Gore & Associates Inc) neochords and ring annuloplasty. Echocardiography revealed a ruptured neochord. During successful mitral valve replacement, the explanted Gore-Tex neochords were found to be stiff and calcified, with a fracture. Electron microscopy was used to examine the explant and a control neochord. There was disruption of the microstructure with extensive calcium infiltration at the fracture point. Although this is a rare cause of late repair failure, it warrants yearly follow-up with echocardiography.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Calcinosis* / etiology
  • Calcinosis* / surgery
  • Female
  • Humans
  • Microscopy, Electron
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / surgery
  • Mitral Valve Insufficiency* / etiology
  • Mitral Valve Insufficiency* / surgery
  • Polytetrafluoroethylene
  • Treatment Outcome

Substances

  • Polytetrafluoroethylene