Characteristic of FINDRISC Score and Association with Diabetes Development in 6-Year Follow-Up in PURE Poland Cohort Study

Vasc Health Risk Manag. 2021 Sep 27:17:631-639. doi: 10.2147/VHRM.S321700. eCollection 2021.

Abstract

Purpose: The aim of the study was to assess if FINDRISC score was associated with diabetes development after 6 years of observation.

Methods: Polish cohort is a part of global PURE study. Hereby analysis presents data from baseline (2007-2010) and 6-year follow-up (2013-2016) and was conducted on 1090 participants (702 women) from urban and rural areas in Lower Silesia region (Poland) without diabetes at the baseline and with complete data throughout course of the study.

Results: At the baseline, women had significantly higher FINDRISC score than men (10.43 vs 8.91; p=0.000) and participants from rural areas had higher score than from urban areas (10.97 vs 9.33; p=0.000). At the baseline, 25.87% of the participants had low risk of diabetes according to FINDRISC score, 38.90% had slightly elevated risk, 16.79% moderate risk, 16.42% high risk and 2.02% very high risk. Participants, who were healthy at baseline, but developed diabetes after 6 years of observation had significantly higher FINDRISC, than those who did not (13.39 vs 9.36; p=0.000). In 6-year follow-up, diabetes was diagnosed in 2.8% of participants, who were ascertained to "low risk" according to FINDRISC score in baseline; in 9.9% of participants of "slightly elevated risk", 17.5% of participants of "moderate risk", 26.8% in participants of "high risk" and 50.0% of participants of "very high risk".

Conclusions: Results of PURE Poland cohort study indicates that higher FINDRISC score at the baseline was associated with higher risk of diabetes development during 6 years of observation.

Keywords: diabetes; epidemiology; preventive medicine.

MeSH terms

  • Body Mass Index
  • Cohort Studies
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Obesity / epidemiology*
  • Overweight / epidemiology
  • Poland / epidemiology
  • Predictive Value of Tests
  • Risk Assessment / methods*
  • Risk Factors
  • Rural Population
  • Urban Population

Grants and funding

The main PURE study and its components are funded by the Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario and through unrestricted grants from several pharmaceutical companies, Poland cohort study is funded by Polish Ministry of Science and Higher Education (grant no. 290/W-PURE/2008/0). Additionally, presented research results, were conducted within the framework of the topic: “Analiza rozpowszechnienia czynników ryzyka chorób cywilizacyjnych w populacji osób dorosłych oraz dzieci w wieku szkolnym z uwzględnieniem miejsca zamieszkania (miasto-wies)” (eng., Study of prevalence of risk factors of noncommunicable diseases in adults and school-aged children considering the place of residence (urban-rural)”) as per records in SIMPLE system number SUB. C. 300.20.033. We declare that funding body had no role in the design of the study, collection, analysis, or interpretation of data and no role in writing the manuscript.