Is Medication-Related Osteonecrosis of the Jaws (MRONJ) Associated to Cyclin-Dependent Kinase (CDK) 4/6 Inhibitors? A Word of Cautiousness. Comment on Marcianò et al. Medication-Related Osteonecrosis of the Jaws and CDK4/6 Inhibitors: A Recent Association. Int. J. Environ. Res. Public Health 2020, 17, 9509

Vittorio Fusco; Manuela Alessio; Pamela Francesca Guglielmini; Maura Vincenti; Antonella Fasciolo; Maura Rossi

doi:10.3390/ijerph181910143

Is Medication-Related Osteonecrosis of the Jaws (MRONJ) Associated to Cyclin-Dependent Kinase (CDK) 4/6 Inhibitors? A Word of Cautiousness. Comment on Marcianò et al. Medication-Related Osteonecrosis of the Jaws and CDK4/6 Inhibitors: A Recent Association. Int. J. Environ. Res. Public Health 2020, 17, 9509

Int J Environ Res Public Health. 2021 Sep 27;18(19):10143. doi: 10.3390/ijerph181910143.

Authors

Vittorio Fusco¹, Manuela Alessio², Pamela Francesca Guglielmini¹, Maura Vincenti¹, Antonella Fasciolo³, Maura Rossi¹

Affiliations

¹ Oncology Unit and Centro Documentazione Osteonecrosi, Azienda Ospedaliera "SS Antonio e Biagio e Cesare Arrigo", 15121 Alessandria, Italy.
² Study CoordinatorOncology Unit, Ospedale "Michele e Pietro Ferrero", 12060 Verduno (CN), Italy.
³ Maxillofacial Surgery Unit, Azienda Ospedaliera "SS Antonio e Biagio e Cesare Arrigo", 15121 Alessandria, Italy.

Abstract

Marcianò et al. launched an alert in this journal about a possible association between medication-related osteonecrosis of the jaws (MRONJ) and cyclin-dependent kinase (CDK) 4/6 inhibitors in breast cancer patients [...].

Publication types

Comment

MeSH terms

Bisphosphonate-Associated Osteonecrosis of the Jaw* / epidemiology
Bisphosphonate-Associated Osteonecrosis of the Jaw* / etiology
Bone Density Conservation Agents*
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinases
Humans
Jaw
Public Health

Substances

Bone Density Conservation Agents
CDK4 protein, human
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinases