Necroptotic and apoptotic cell death in Toxic Epidermal Necrolysis

J Dermatol Sci. 2021 Nov;104(2):138-141. doi: 10.1016/j.jdermsci.2021.09.005. Epub 2021 Sep 23.

Authors

Pia-Charlotte Stadler¹, Benjamin M Clanner-Engelshofen², Doris Helbig³, Takashi Satoh², Markus Reinholz², Lars E French⁴

Affiliations

¹ Department of Dermatology and Allergy, University Hospital, LMU Munich, Germany. Electronic address: [email protected].
² Department of Dermatology and Allergy, University Hospital, LMU Munich, Germany.
³ Department of Dermatology, University Hospital Cologne, Germany.
⁴ Department of Dermatology and Allergy, University Hospital, LMU Munich, Germany; Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami, Miller School of Medicine, Germany.

PMID: 34656387
DOI: 10.1016/j.jdermsci.2021.09.005

No abstract available

Publication types

Letter

MeSH terms

Apoptosis*
Biopsy
Caspase 3 / metabolism
Caspase 8 / metabolism
Epidermis / metabolism
Epidermis / pathology*
Humans
Keratinocytes / metabolism
Keratinocytes / physiology*
Necroptosis*
Protein Kinases / metabolism
Receptor-Interacting Protein Serine-Threonine Kinases / metabolism
Stevens-Johnson Syndrome / metabolism
Stevens-Johnson Syndrome / pathology*

Substances

MLKL protein, human
Protein Kinases
RIPK3 protein, human
Receptor-Interacting Protein Serine-Threonine Kinases
Caspase 3
Caspase 8