CEACAM7 polymorphisms predict genetic predisposition to mortality in post-surgical septic shock patients

J Microbiol Immunol Infect. 2022 Jun;55(3):540-544. doi: 10.1016/j.jmii.2021.09.006. Epub 2021 Oct 8.

Abstract

We carried out a retrospective exploratory study on 173 patients who underwent major surgery and developed septic shock after surgery. Our findings suggest that CEACAM7 rs1001578, rs10409040, and rs889365 polymorphisms could influence septic shock-related death in individuals who underwent major surgery.

Keywords: CEACAM7; Major surgery; SNPs; Septic shock; Survival.

MeSH terms

  • Carcinoembryonic Antigen* / genetics
  • GPI-Linked Proteins* / genetics
  • Genetic Predisposition to Disease
  • Humans
  • Polymorphism, Genetic
  • Retrospective Studies
  • Shock, Septic* / genetics

Substances

  • CEACAM7 protein, human
  • Carcinoembryonic Antigen
  • GPI-Linked Proteins