Liver graft outcomes from donors with vaccine induced thrombosis and thrombocytopenia (VITT): United Kingdom multicenter experience

Angus Hann; Hermien Hartog; Anisa Nutu; Katherine Quist; Rebecca Sanabria-Mateos; George H B Greenhall; Ines Ushiro-Lumb; Phillip L R Nicolson; Owen Cain; Ye H Oo; Abhishek Chauhan; Will Lester; Joerg-Matthias Pollok; Andreas Prachalias; John R Isaac; Douglas Thorburn; John Forsythe; Khalid Sharif; Desley A H Neil; Darius F Mirza; M Thamara P R Perera

doi:10.1111/ajt.16869

Liver graft outcomes from donors with vaccine induced thrombosis and thrombocytopenia (VITT): United Kingdom multicenter experience

Am J Transplant. 2022 Mar;22(3):996-998. doi: 10.1111/ajt.16869. Epub 2021 Oct 29.

Authors

Angus Hann^{1

2}, Hermien Hartog^{1

3}, Anisa Nutu¹, Katherine Quist⁴, Rebecca Sanabria-Mateos⁵, George H B Greenhall⁶, Ines Ushiro-Lumb⁶, Phillip L R Nicolson⁷, Owen Cain⁸, Ye H Oo^{1

2}, Abhishek Chauhan^{1

2}, Will Lester⁷, Joerg-Matthias Pollok^{4

9}, Andreas Prachalias⁵, John R Isaac¹, Douglas Thorburn^{4

6}, John Forsythe⁶, Khalid Sharif³, Desley A H Neil^{2

7}, Darius F Mirza^{1

2

3}, M Thamara P R Perera^{1

3}

Affiliations

¹ Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
² Centre for liver and gastrointestinal research, Institute of Immunology and Immunotherapy, NIHR Birmingham BRC, University of Birmingham, Birmingham, UK.
³ Birmingham Children's Hospital, Birmingham, UK.
⁴ Liver Unit, Royal Free Hospital, London, UK.
⁵ Liver Unit, Kings College Hospital, London, UK.
⁶ National Health Service Blood and Transplant Service, Bristol, UK.
⁷ Department of Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
⁸ Department of Pathology, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
⁹ Department of surgery & Interventional Science, University College London, London, UK.

PMID: 34662508
DOI: 10.1111/ajt.16869

No abstract available

Keywords: alloantibody; autoimmunity; clinical research/practice; donors and donation: donor evaluation; ethics and public policy; liver allograft function/dysfunction; liver transplantation/hepatology; organ procurement and allocation; pathology/histopathology; vaccine.

Publication types

Letter
Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Graft Survival
Humans
Liver
Thrombocytopenia* / chemically induced
Thrombosis* / etiology
Tissue Donors
Tissue and Organ Procurement*
Vaccines*

Substances

Vaccines