Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation

Natl Sci Rev. 2020 Nov 24;8(2):nwaa285. doi: 10.1093/nsr/nwaa285. eCollection 2021 Feb.

¹ Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, China.
² Center for Cell Fate and Lineage (CCLA), Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), China.
³ CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, China.
⁴ Kunming National High-level Biosafety Research Center for Non-human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology Chinese Academic of Sciences, China.
⁵ Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Germany.

No abstract available