Long-term efficacy and adverse effects of outpatient procedural analgesia with nitrous oxide for a child with Epidermolysis Bullosa

Paediatr Anaesth. 2022 Jan;32(1):85-87. doi: 10.1111/pan.14318. Epub 2021 Nov 7.

Abstract

Epidermolysis Bullosa is a dermatologic condition characterized by skin fragility and the formation of painful blisters all over the body. The course of this chronic hereditary disorder involves multiple painful procedures for which adequate analgesia is an ongoing challenge. This case report follows a previously-described pediatric patient with the Dowling-Meara variant of Epidermolysis Bullosa who was treated with at-home nitrous oxide for daily procedural analgesia. We report on the long-term effectiveness of this treatment in addition to any side effects encountered as a result of this treatment.

Keywords: Epidermolysis Bullosa; adverse effects; chronic pain; nitrous oxide; pediatrics; procedural analgesia.

Publication types

  • Case Reports

MeSH terms

  • Analgesia*
  • Child
  • Epidermolysis Bullosa* / complications
  • Humans
  • Nitrous Oxide
  • Outpatients
  • Pain Management

Substances

  • Nitrous Oxide