Ventilatory Strategies in Infants with Established Severe Bronchopulmonary Dysplasia: A Multicenter Point Prevalence Study

Robin L McKinney; Natalie Napolitano; Jonathan J Levin; Matthew J Kielt; Steven H Abman; Milenka Cuevas Guaman; Rebecca S Rose; Sherry E Courtney; David Matlock; Amit Agarwal; Kristen T Leeman; Lauren A Sanlorenzo; Richard Sindelar; Joseph M Collaco; Christopher D Baker; Kathleen E Hannan; Matthew Douglass; Laurie C Eldredge; Khanh Lai; Sharon A McGrath-Morrow; Michael C Tracy; William Truog; Tamorah Lewis; Anarina L Murillo; Martin Keszler; BPD Collaborative

doi:10.1016/j.jpeds.2021.10.036

Ventilatory Strategies in Infants with Established Severe Bronchopulmonary Dysplasia: A Multicenter Point Prevalence Study

J Pediatr. 2022 Mar:242:248-252.e1. doi: 10.1016/j.jpeds.2021.10.036. Epub 2021 Oct 26.

Authors

Robin L McKinney¹, Natalie Napolitano², Jonathan J Levin³, Matthew J Kielt⁴, Steven H Abman⁵, Milenka Cuevas Guaman⁶, Rebecca S Rose⁷, Sherry E Courtney⁸, David Matlock⁸, Amit Agarwal⁹, Kristen T Leeman³, Lauren A Sanlorenzo¹⁰, Richard Sindelar¹¹, Joseph M Collaco¹², Christopher D Baker⁵, Kathleen E Hannan¹³, Matthew Douglass¹⁴, Laurie C Eldredge¹⁵, Khanh Lai¹⁴, Sharon A McGrath-Morrow¹⁶, Michael C Tracy¹⁷, William Truog¹⁸, Tamorah Lewis¹⁸, Anarina L Murillo¹⁹, Martin Keszler²⁰; BPD Collaborative

Affiliations

¹ Division of Pediatric Critical Care Medicine, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI. Electronic address: [email protected].
² Department of Respiratory Care, Children's Hospital of Philadelphia, Philadelphia, PA.
³ Division of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA.
⁴ Comprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH.
⁵ Section of Pulmonary and Sleep Medicine, Pediatric Heart Lung Center, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
⁶ Division of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, TX.
⁷ Department of Neonatology, Indiana University School of Medicine, Indianapolis, IN.
⁸ Section of Neonatology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AK.
⁹ Section of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AK.
¹⁰ Division of Neonatology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
¹¹ Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
¹² Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.
¹³ Section of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
¹⁴ Division of Pediatric Pulmonary and Sleep Medicine, University of Utah, Salt Lake City, UT.
¹⁵ Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA.
¹⁶ Division of Pulmonary Medicine and Sleep, Children's Hospital of Philadelphia, Philadelphia, PA.
¹⁷ Division of Pediatric Pulmonary, Asthma and Sleep Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
¹⁸ Center for Infant Pulmonary Disorders, Children's Mercy, Kansas City, MO.
¹⁹ Center for Statistical Sciences, School of Public Health, Brown University, Providence, RI.
²⁰ Division of Neonatology, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI.

Abstract

We performed a point prevalence study on infants with severe bronchopulmonary dysplasia (BPD), collecting data on type and settings of ventilatory support; 187 infants, 51% of whom were on invasive positive-pressure ventilation (IPPV), from 15 centers were included. We found a significant center-specific variation in ventilator modes.

Keywords: BPD; chronic lung disease; chronic mechanical ventilation; neonatology.

Publication types

Case Reports
Multicenter Study

MeSH terms

Bronchopulmonary Dysplasia* / epidemiology
Bronchopulmonary Dysplasia* / therapy
Humans
Infant
Infant, Newborn
Prevalence
Ventilators, Mechanical

Abstract

Publication types

MeSH terms

Grants and funding